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International Journal of Pharmacology
Year: 2010  |  Volume: 6  |  Issue: 4  |  Page No.: 425 - 430

The Obtaining of an Antioxidant Product Based on a Rosmarinus officinalis Freeze-Dried Extract

V. Emanuel, V. Adrian and Nita Sultana    

Abstract: The aim of this study was to obtain a freeze-dried extract with an important antioxidant and antimicrobial effect from Rosmarinus officinalis. The extracts were obtained in a fluidized bed solid extractor and there has resulted that the optimal values of phenols, flavonoids and the highest reduction power were determined when using 70% ethanol as solvent, the antioxidant activity ranging between 90-95%. In case of the freeze-dried product, the maximum antioxidant activity was registered when using 0.2 mg mL-1 powder and the results were optimal as well in case of determining flavonoids, phenols and the reduction power. The antimicrobial effect of the extracts and of the freeze-dried product were quantified by using the Colony Quant software on the strains Escherichia coli CBAB 2, Bacillus cereus CMGB 215, Listeria innocua CMGB 218. An inhibition area of maximum 2 cm resulted when using 70% ethanol as solvent. The optimal inhibitory effect of the freeze-dried product, of around 1.8 cm, was determined by a 0.2 mg mL-1 concentration.

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