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International Journal of Pharmacology
Year: 2010  |  Volume: 6  |  Issue: 4  |  Page No.: 372 - 378

Effects of Methyl and Methoxy Derivatives of Phencyclidine on Food and Water Intake

J. Solati, A. Ahmadi and A.A. Salari    

Abstract: The present study examined whether administration of PCP and its methyl and methoxy derivatives affect food and water intake under deprivation. Animals were deprived for 24 h before tested for food and water intake. The PCP and its derivatives were injected intraperitoneally and treated groups measured 1-12 h for food and 30-180 min for water intake post-injection. The results showed that, both of derivatives, can increase food and water intake in comparison to the PCP and saline groups. Methyl and methoxy derivatives of phencyclidine may affect central systems that are involved in feeding behavior.

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