Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
International Journal of Pharmacology
Year: 2009  |  Volume: 5  |  Issue: 3  |  Page No.: 228 - 231

Evaluating the Antibacterial Activity and in vivo Assay of Methanolic Extract of Stichopus badionotus

N.S. Mariana, M.A. Norfarrah, K.A.N.I. Nik, F.M. Yusoff and A. Arshad    

Abstract: This study investigated the antibacterial activity of the methanolic extract of the animal to justify its use in traditional medicine. Antimicrobial activity was assayed by disc diffusion method and broth macro dilution method. From the result it appeared that the methanolic extract of Stichopus badionotus displayed antibacterial activities against Staphylococcus aureus, three non resistant strains and three multiple resistant strains. The Minimum Inhibitory Concentration (MIC) of the extract against non resistant strain values were 3.75 mg mL -1 and for resistant strain values 7.50 mg mL -1. Further more, this extract tested on rats in wound infection model justified faster healing rates compared to antibiotics. These results indicate that the traditional use of these holothurians for the treatment of S. aureus infection mainly on resistant strains should be elucidate to bring out the potential antibacterial agent.

Cited References   |    Fulltext    |   Related Articles   |   Back
   
 
 
 
  Related Articles

 
 
 
 
 
 
 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility