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International Journal of Pharmacology

Year: 2008  |  Volume: 4  |  Issue: 3  |  Page No.: 230 - 232

Potential Antimicrobial Activity of Various Extracts of Bacopa monnieri (Linn.)

P. Sampathkumar, B. Dheeba, V. Vidhyasagar, T. Arulprakash and R Vinothkannan

Abstract

The present study was carried out to evaluate the antimicrobial potential of ethanolic, diethyl ether, ethyl acetate and aqueous extracts of aerial parts of Bacopa monnieri (L.). The antimicrobial activity of ethanolic, diethyl ether, ethyl acetate tested for the Staphylococcus aureus, Proteus vulgaris, Candida albicans and Aspergillus niger. Diethyl ether extracts of Bacopa monnieri showed an antibacterial activity against gram positive and ethyl acetate extract was active against gram negative organism. The extract of diethyl ether having potent antimicrobial activity against Staphylococcus aureus at higher concentrations (300 μg mL-1). Ethanolic extract of Bacopa monnieri has more antifungal activity against Candida albicans and Aspergillus niger. Diethyl ether extract and Ethyl acetate extract has slight antifungal activity but have broad spectrum of antibacterial effect against the entire tested organisms, whereas ethanolic extract showed marked inhibitory activity against fungal species. Aqueous extract of the different concentration showed no inhibitory effects on the tested microorganisms due to loss of some active compounds during extraction processes of the sample.

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