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International Journal of Pharmacology

Year: 2006  |  Volume: 2  |  Issue: 1  |  Page No.: 24 - 27

The Tissue Kinetics and Residues of Chloramphenicol in Sokoto Red Goats

E.U. Etuk and P.A. Onyeyili

Abstract

The kinetics and residue of chloramphenicol in the various tissues of the Sokoto red goats has been studied using colorimetric assay method. The results indicate that, Variable concentrations of chloramphenicol were detected 5 min after a single intravenous dose of the drug (25 mg kg 1) in various tissues of the animal. The drug persisted up to 240 h (10 days) in the skeletal muscle of the goats. The kinetics of the drug also show variation among the various tissues considered. These findings are of public health significance.

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