Anti-Cancer Effect of Indirubin-3'-Monoxime for Human Laryngeal Carcinoma
The present investigation made in documenting the in vitro anti-proliferative activity of indirubin-3-monoxime on human epithelial larynx cell line (Hep-2 cells). The Indirubin propensity for anti-proliferative effects was studied and its mechanism of action was documented using the techniques Trypan blue staining, MTT assay and propidium iodide staining. We observed a dose dependent cell death on treatment with indirubin-3-monoxime. On the basis of results, we concluded, indirubin-3-monoxime inhibits the proliferation of Human laryngeal cancer cells (Hep-2).
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