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International Journal of Cancer Research

Year: 2008  |  Volume: 4  |  Issue: 4  |  Page No.: 110 - 126

Malignancies in Clitoris: A Review of Literature on Etiology, Diagnosis, Pathology and Treatment Strategies

M. Mashael Al-Shebaily and Viquar Fatima Qureshi


The present study is an attempt to review literature on etiology, clinical presentation, diagnosis, pathogenesis and treatment strategies of clitoral cancer. The review emphasizes on different etiological factors represented by clinical presentations, such as infective organisms, circumcision, infibulation, clitoromegaly, priapism, vulvar cancers, ovarian cancers, mixed gonadal dysgenesis, metastasis from cancers of distant organs (adrenal glands, urinary bladder and rectal cancer), neurofibromatosis and other etiologies of tumors growing on clitoris. The diagnostic approach and pathology are interwoven on different aspects of clinical findings. The treatment strategies, including clitoridectomy, clitoroplasty, vulvectomy, lymphadenectomy, CO2-laser treatment, laser vaporization, combined roentgenotherapy, deep x-ray irradiation and treatment for mixed gonadal dysgenesis are reviewed. This review demonstrates that there is an imperative need for more work related with case reports and review articles on malignancies of clitoris.

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