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International Journal of Biological Chemistry
Year: 2012  |  Volume: 6  |  Issue: 2  |  Page No.: 53 - 60

Potentiality Test in Antimicrobial Activity and Antibiotic Sensitivity of Subterranean Streptomyces Strains Isolated from Kotumsar Cave of India

Yogita Rajput, Jayant Biswas and Vibhuti Rai    

Abstract: The almost high and stable environmental factors always represent a subterranean cave as one of the most vulnerable environments on Earth. In such conditions, the microbial communities that survive definitely reveal strong antimicrobial and other relevant biological activities. In the present study, the antimicrobial activity and the antibiotic sensitivity of seven Streptomyces strains isolated from various depth dependent microhabitats of a subterranean cave has been tested. Antimicrobial activity was found maximum against E. coli than Staphylococcus aureus and Pseudomonas aeruginosa. Further, the strains isolated from the deeper habitats of the cave have revealed much antagonistic activities as compared to the strains of anterior habitats. Some interesting results have also been revealed from antibiotic sensitivity tests which altogether indicate the possibilities for occurrence of high potential Streptomyces strains from this particular cave, useful for biotechnological tools.

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