Abstract: Field experiment was conducted to investigate the effect of intra row spacing and time of earthing up on growth and yield of potato (var. Jalene). Four intra row spacing: 10, 20, 30 and 40 cm and four times of earthing up: At 15, 30, 45 days after plant emergence and no earthing were combined in a 4x4 factorial arrangement in randomized complete block design. Data collected on growth and yield parameters were analyzed using SAS version 9.2. Intra row spacing highly significantly affected all the growth parameters: days to 50% flowering and maturity, plant height and spread, stem diameter and leaf area and all yield parameters: Tuber number, total and marketable tuber yield. For majority of growth and yield parameters 40 and 30 cm intra row spacing was preferable, while significantly the highest marketable tuber yield of 23.54 t ha^-1 was produced at 30 cm intra row spacing. The effect of time of earthing up was found highly significant on all growth parameters studied: days to 50% flowering and maturity, plant height and spread, stem diameter, leaf area and main stem number and all yield parameters studied: Tuber number, total and marketable tuber yield. Earthing up at 15 days after plant emergence showed superior performance in most growth and yield parameters. Therefore, 30 cm intra row spacing and earthing up at 15 days after complete plant emergence can be used at the study area, Boneya in Degem district for better growth and higher marketable yield of potato.