Asian Science Citation Index is committed to provide an authoritative, trusted and significant information by the coverage of the most important and influential journals to meet the needs of the global scientific community.  
ASCI Database
308-Lasani Town,
Sargodha Road,
Faisalabad, Pakistan
Fax: +92-41-8815544
Contact Via Web
Suggest a Journal
European Journal of Dentistry and Medicine
Year: 2016  |  Volume: 8  |  Issue: 1-3  |  Page No.: 12 - 16

Effects of Malus domestica Fruit Extracts Against Clinically Isolated Dental Pathogens

J. Anbu Jeba Sunilson, A.V. Anita Gnana Kumari, Abdullah Khan and K. Anandarajagopal    

Abstract: Background and Objective: Medicinal plants have a vital role in the development of novel antimicrobial agents. The fruit Malus domestica is known as apple and commonly used to prevent tooth decay by killing dental pathogens. However, there were no scientific reports about the fruits of Malus domestica having antimicrobial activity against dental pathogens. The aim of this study was to extract the active constituents present in the fruits of Malus domestica by cold maceration method using petroleum ether, ethanol and water. Methodology: The antibacterial activity was assessed by cup plate method against five isolated dental pathogens such as Staphylococcus aureus, Streptococcus mutans, Lactobacillus subtilis, Klebsiella sp. and Pseudomonas sp. and the radial zone of inhibition was measured. Results: The results revealed that the ethanol extract (100 mg mL–1) has more potent antibacterial activity against S. aureus, S. mutans and Pseudomonas sp., followed by aqueous extract (100 mg mL–1) whereas, petroleum ether extract (100 mg mL–1) has not shown any zone of inhibition against the tested microorganisms. All the results were compared with standard drug chlorhexidine 0.2% w/v. Conclusion: Hence, the study concludes that Malus domestica fruit extracts possess significant (p<0.001, p<0.01, p<0.05) antibacterial activity against dental pathogens. The phyto chemical tests on ethanol extract showed the presence of bioactive constituents such as terpenoids, flavonoids, phenolic compounds and tannins which could be responsible for the antibacterial activity of M. domestica fruit.

Cited References   |    Fulltext    |   Related Articles   |   Back
   
 
 
 
  Related Articles

 
 
 
Copyright   |   Desclaimer   |    Privacy Policy   |   Browsers   |   Accessibility