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European Journal of Dentistry and Medicine
Year: 2009  |  Volume: 1  |  Issue: 1  |  Page No.: 1 - 7

Anticaries Effects of Baphia nittida Extract in Albino Rats

E.S. Amadi, C.A. Oyeka, I. Okoli, J.I. Ihedioha and I.R. Iroha    

Abstract: The possible curative and preventive effect of Baphia nittida extract on insipient caries and caries-free rats were investigated. About 200 mg mL-1 of Baphia nittida extract were intra-orally administered to the teeth surfaces of different rat groups. Evidence of development of caries was determined by direct observation, probing, microbial count and radiography. The result of the study showed that there was no evidence of dental caries among the non-insipient caries rat groups fed simultaneously with 70% sucrose-in-diet and extract of Baphia nittida. Similarly, the rat groups having insipient caries did not exhibit signs of dental caries after the administration of Baphia nittida extract. There was a significant difference (p<0.05) between the pre and post microbial count of the insipient caries rat groups given Baphia nittida extract. Also, there was a significant difference (p<0.05) between the pre and post microbial count of the caries-free rat groups given Baphia nittida extract twice daily. The result generally suggested that Baphia nittida extract has in vivo preventive and curative potential on dental caries in rats simultaneously fed with 70% sucrose-in-diet.

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