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Eastern Mediterranean Health Journal
Year: 2008  |  Volume: 14  |  Issue: 3  |  Page No.: 628 - 635

Outcome and management of pregnancy in women with thalassaemia in Cyprus

Toumba M., Kanaris C., Simamonian K. and Skordis N.    

Abstract: We describe the management and clinical outcome of pregnancies among 100 Greek Cypriot women with thalassaemia: 88 with thalassaemia major and 12 with thalassaemia intermedia. A total of 152 successful pregnancies and 161 deliveries were included. All patients had endocrine assessment and frequent ferritin measurements. Multiple successful pregnancies included 7 twins and 1 triple pregnancy. Pregnant thalassaemics required significantly larger amount of total blood transfusion during pregnancy. There was a statistically significant increase in the ferritin levels during pregnancy, and levels remained significantly higher after pregnancy. Most pregnancies resulted in delivery of full-term healthy babies, and obstetric complications were rare, although some problems were encountered.

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