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Year: 2009 | Volume: 195 | Issue: 5 | Page No.: 408 - 413
T. N Akbaraly, E. J Brunner, J. E Ferrie, M. G Marmot, M Kivimaki and A. Singh Manoux
Abstract
Background
Studies of diet and depression have focused primarily on individual nutrients.
Aims
To examine the association between dietary patterns and depression using an overall diet approach.
Method
Analyses were carried on data from 3486 participants (26.2% women, mean age 55.6 years) from the Whitehall II prospective cohort, in which two dietary patterns were identified: ‘whole food’ (heavily loaded by vegetables, fruits and fish) and ‘processed food’ (heavily loaded by sweetened desserts, fried food, processed meat, refined grains and high-fat dairy products). Self-reported depression was assessed 5 years later using the Center for Epidemiologic Studies – Depression (CES–D) scale.
Results
After adjusting for potential confounders, participants in the highest tertile of the whole food pattern had lower odds of CES–D depression (OR = 0.74, 95% CI 0.56–0.99) than those in the lowest tertile. In contrast, high consumption of processed food was associated with an increased odds of CES–D depression (OR = 1.58, 95% CI 1.11–2.23).
Conclusions
In middle-aged participants, a processed food dietary pattern is a risk factor for CES–D depression 5 years later, whereas a whole food pattern is protective.