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Biotechnology
Year: 2018  |  Volume: 17  |  Issue: 2  |  Page No.: 62 - 68

Evaluate the Effect of Inhibiting Pathogenic Bacteria and Fungus of Eczematous Dermatitis and Antioxidant Activity of Phenolic from Qinglicao (Polygonum chinense L. Var. chinense)

Xudong Jiang, Weiguang Wang, Xiaoting Huang, Axiang Song, Lujiao Lu, Xiaoling Lu and Gang Wu    

Abstract: Background: QingLiCao has been used for the treatment of skin diseases such as eczematous dermatitis in China-Vietnam border area. However, the mechanism of treatment effect is still unclear. This study aimed to investigate the inhibitory effect of pathogenic bacteria and fungus of eczematous dermatitis and evaluate the antioxidant activity of phenolic contents from QingLiCao, will be helpful to further understand the mechanism of action. Materials and Methods: The in vitro phenolic antimicrobial activity was determined using disc diffusion and antioxidant activity was evaluated by spectrophotometry. Results: The experimental results showed that the phenolics from QingLiCao had excellent antimicrobial activity to pathogenic bacteria and fungus of eczematous dermatitis, similar results were observed for the antioxidant activity. Conclusion: The results support the proposition that phenolic from QingLiCao might be a promising anti-eczematous dermatitis natural active ingredients merit further investigations.

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