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Anesthesia & Analgesia
Year: 2009  |  Volume: 108  |  Issue: 6  |  Page No.: 1941 - 1943

Vasoplegic Syndrome During Liver Transplantation

Z Cao, Y Gao and G. Tao    


A 56-yr-old woman with chronic hepatitis B and decompensated hepatic cirrhosis was treated with liver transplantation. At the beginning of the neohepatic phase, her arterial blood pressure remained at 60/40 mm Hg for approximately 40 min and did not respond to vasoconstrictive drugs. Her other clinical and laboratory values remained normal, apart from a high cardiac output and low systemic vascular resistance. This patient was diagnosed with vasoplegic syndrome and was treated with IV infusion of methylene blue (0.5 mg/kg) and norepinephrine. This report has potential significance to treatment in patients who undergo orthotopic liver transplantation.

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