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Asian Journal of Scientific Research

Year: 2016  |  Volume: 9  |  Issue: 3  |  Page No.: 122 - 125

Effect of Plasmodium falciparum Infection on Serum Levels of Calcium, Magnesium, Zinc and Iron Among Adult Sudanese Patients

Kamal Eldin Ahmed Abdelsalam


Background: The effect of Plasmodium falciparum infection on the elements (Ca, Mg, Zn and Fe) was determined in adult Sudanese patients. Materials and Methods: This study included 75 normal healthy volunteers as control group, 75 infected patients with Plasmodium falciparum. Diagnosis was done by immunochromatographic test specific for Plasmodium falciparum as well as by thick and thin blood film. The serum specimens were used to measure magnesium (Mg) and iron (Fe) concentrations using a Hitachi 912 Chemistry Analyzer as per manufacturer’s procedure. The calcium (Ca) and zinc (Zn) levels were measured by atomic absorption spectrometry. Results: In the present study, significant decrease ib levels of Mg, Fe and Ca was observed in infected patients when compared to controls (p = 0.000). This study showed that whenever the density of the parasites in the blood increased, there was a significant reduction of Fe, Zn and Ca concentration (p<0.05). The Mg and Fe in infected males increased significantly (p = 0.033 and p = 0.000, respectively) while Zn levels decreased significantly in infected males when compared to infected females (p = 0.000). Conclusion: It was concluded that Plasmodium falciparum infection reduced Mg, Fe and Ca significantly when compared to non-infected control. The levels of serum Fe and Zn were significantly decreased as increasing in the parasitaemia.

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