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Asian Journal of Scientific Research
Year: 2008  |  Volume: 1  |  Issue: 3  |  Page No.: 281 - 287

Effect of FSH+LH (Pergonal®) Treatments on Hormonal Profile and Superovulatory Response of West African Dwarf Does

F.C. Iheukwumere, A.H. Abu and I.C. Okoli    

Abstract: The effect of the administration of varying doses of FSH+LH (Pergonal®, Ferring Labs, USA) was used on 16 clinically, sound, parous, West African dwarf does aged 2-3 years to evaluate the hormonal profiles and superovulatory responses. Four treatment groups were employed consisting of T1 (administered with physiological saline as the control), T2, T3 and T4 given 19.0 IU, 58.0 IU and 82.0 IU FSH+LH, respectively, as intramuscular injections over 3 days. The results on the number of corpora lutea found on the ovary did not show any significant difference (p>0.05) between goats on T2 (5.25±2.74) T3 (6.25±2.13) and T4 (6.50±2.74). However, they differed significantly (p<0.05) from goats on T1 (3.75±0.30) in the number of corpora lutea on the ovary. The number of embryos recovered was not significantly different (p>0.05) between goats on T2 (4.50±0.93), T3 (4.70±0.86) and T4 (4.75±1.27). However, they differed significantly (p<0.05) from goats on T1 (2.25±0.01) in number of embryos recovered. Goats treated on T2 with embryo recovery rate (78.30±0.18%) did not differ significantly (p>0.05) from goats on T3 (75.20±0.14%) and T4 (73.10±0.06%). However, they differed significantly (p<0.05) from goats on T1 (60.00±0.02%). The ova/embryo wastage was not significantly different (p>0.05) between goats on T2 (21.70±0.30%), T3 (27.80±0.12%) and T4 (26.90±0.16%). However, they differed significantly (p<0.05) from goats on T1 (40.00±0.01%) in embryo wastage. LH and FSH were highest at T3 treatment group with values of (3.60±0.02 and 3.13±0.14 (IU L-1), respectively. Progesterone and Oestradiol showed higher values on T4 goats with (16.17±1.01 and 0.26±0.41 nmmol L-1), respectively. The results of this study indicate that the administration of FSH+LH enhanced embryo production and hormonal levels in West African dwarf goats.

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