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Asian Journal of Plant Sciences

Year: 2011  |  Volume: 10  |  Issue: 1  |  Page No.: 86 - 91

Evaluation of Therapeutic Potential of Traditionally Consumed Cucumis melo Seeds

N.S. Gill, J. Bajwa, K. Dhiman, P. Sharma, S. Sood, P.D. Sharma, B. Singh and M. Bali

Abstract

The objective of present study was to evaluate the therapeutic potential of Cucumis melo seeds traditionally consumed and it was studied for free radical scavenging potential by hydrogen peroxide (H2O2) and DPPH method. Anti-inflammatory activity was evaluated using carrageenan-induced paw edema in rats. Analgesic activity was evaluated by tail immersion and tail flick methods in mice. The percentage scavenging of DPPH radical and H2O2 radical was 74.9% at 300 μg mL-1 and 58.91% at 200 μg mL-1 respectively concentration of. The H2O2 scavenging effect of MECM was 58.91%. The percentage reduction of paw edema was 56.6% at the dose of 300 mg kg-1. The high dose caused significant reduction in pain. Thus it can be concluded from the above results that Cucumis melo seeds have potent anti-inflammatory, antioxidant and analgesic activity.

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