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Asian Journal of Plant Sciences
Year: 2005  |  Volume: 4  |  Issue: 4  |  Page No.: 429 - 434

Prevalence of Penicillium chrysogenum, its Qualitative, Quantitative Determination and Antibacterial Activity in Indian Soil

Amit Kumar, Richa Kaushik, Ekta Varshney, Anjana Kashyap and Manoj Kumar Kashyap    

Abstract: The present study was designed to a systematic screening for the potential isolates of P. chrysogenum from Indian soils (Haridwar and Dehradun districts of Uttaranchal state) and their antibacterial activity (quantitative and qualitative analysis). Total 329 soil isolates of P. chrysogenum were isolated from 120 collected soil samples (Agricultural, Garden and Road soil) from Haridwar (40.12%) and Dehradun (59.87%) districts during the months of May-June and September-October, 2002. All P. chrysogenum soil isolates showed remarkable antibacterial activity against S. epidermidis (MTCC-435) as test strain. Besides this penicillin G production by P. chrysogenum isolates was found with a total positivity from Haridwar (87.39%) and Dehradun (89.78%). Finally, these isolates were confirmed for penicillin G production by HPLC. We observed that agricultural soil is a major source for potential isolates of P. chrysogenum as compared to garden and road soils.

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