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Asian Journal of Plant Sciences
Year: 2004  |  Volume: 3  |  Issue: 1  |  Page No.: 61 - 64

Antibacterial Activity of Some Medicinal Plants of Iran Against Pseudomonas aeruginosa and P. fluorescens

G.H. Shahidi Bonjar and A. Karimi Nik    

Abstract: Increase of antibacterial resistance is a global growing-problem. Isolation of microbial agents less susceptible to regular antibiotics and recovery of increasing resistant isolates during antibacterial therapy is rising throughout the world which highlights the need for new principles. In treating burns, dermatophytes and infectious diseases, use of plants is common in traditional medicine of Iran. According to the collected information about herbal remedies of such plants, antibacterial activities of methanol extracts of the plants were determined by in vitro bioassays using agar diffusion-method against standard strains of Pseudomonas aeruginosa and P. fluorescens at 20 mg ml-1. From 160 plant species in 65 families, 13 species (8.1%) in 12 families (18.4%) showed anti-Pseudomona activities. Activities included 6.2% against P. aeruginosa and 7.5% against P. fluorescens. Minimum inhibitory concentrations (MIC) of the actives were determined using two fold serial dilutions. Most active plants against both bacterial species were Dianthus caryophyllus L., Terminalia chebula (Gaertner) Retz. and Myrtus communis L. with the MIC of 3.75, 1.87 and 7.5 mg ml-1 against P. aeruginosa; 0.46, 0.93 and 1.87 mg ml-1 against P. fluorescens, respectively.

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