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Asian Journal of Biological Sciences
Year: 2019  |  Volume: 12  |  Issue: 3  |  Page No.: 477 - 481

Sperm Profile and Testicular Weight Assessment of Albino Rats Administered African Nutmeg (Monodora myristica) and African Basil (Ocimum gratissimum)

Lawrence Enyioha Okonko, Ekei Victor Ikpeme and Success Eni Kalu    

Abstract: Background and Objectives: Monodora myristica and Ocimum gratissimum are herbs widely consumed for nutritional and medicinal purposes in developing countries including Nigeria. This study was therefore designed to assess the effects of M. myristica and O. gratissimum on sperm parameters, testicular and epididymal weight of albino rats. Materials and Methods: Forty-nine male Albino rats (170-200 g) were divided randomly into 7 groups (A-G) of 7 animals each. Rats in group A served as the control; groups B and C were given 300 and 500 mg kg–1 b.wt., of M. myristica, respectively; groups D and E received 300 and 500 mg kg–1 b.wt., of O. gratissimum, respectively; while groups F and G received 300 and 500 mg kg–1 b.wt., of M. myristica+ O. gratissimum, respectively. After 8 weeks of treatment, the animals were sacrificed and sperm samples collected for analysis. Results: Sperm analysis revealed that extract of M. myristica increased epididymal sperm motility, viability and count significantly (p<0.05) and dose dependently; whereas extract of O. gratissimum and the combined plant extract reduced sperm motility, viability and count significantly. Extract of O. gratissimuma lone increased sperm head abnormalities significantly. Conclusion: Findings of this study therefore, suggest that M. myristica promotes male fertility, whereas O. gratissimum and the combination of both herbs could have anti-fertility effects.

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