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Asian Journal of Biological Sciences
Year: 2014  |  Volume: 7  |  Issue: 2  |  Page No.: 72 - 75

Picrorhiza kurrooa Royal Ex Benth Exhibits Antimalarial Activity against Plasmodium berghei Vincke and Lips, 1948

H.S. Banyal, Rani and Nisha Devi    

Abstract: Different parts of Picrorhiza kurrooa (Kutki) were used to evaluate their antimalarial effect against Plasmodium berghei in vivo in a typical 4 day test. Experimental groups of mice were administered with ethanol extracts of roots and leaves of Picrorhiza kurrooa. On day 4 parasitaemia in control group of mice was 23.15±1.66 whereas, groups treated with roots and leaves extract of P. kurrooa resulted in inhibition of malaria parasite significantly and parasitaemia being 4.14±1.70 and 11.4±1.66, respectively. The effect of root extract was more pronounced compared to leaves.

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