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Asian Journal of Biological Sciences
Year: 2008  |  Volume: 1  |  Issue: 2  |  Page No.: 94 - 99

Chronic Lung Disease of the Malaysian Premature Neonates is not Associated with Ureaplasma urealyticum and Mycoplasma

Kek Heng Chua, Suzita Mohd Noor, Ching Hoong Chew and Chin Theam Lim    

Abstract: Mortality rate in the preterm neonate is believed to be associated with the chronic lung disease (CLD) and CLD is mainly caused by the infections of either Ureaplasma urealyticum or Mycoplasma horminis based on other studies. Therefore in this research, endotracheal aspirates of 57 intubated Malaysian premature neonates were used to study the association between colonization of Ureaplasma urealyticum or Mycoplasma in the respiratory tract of preterm neonates with subsequent development of chronic lung disease using Mycofast® screening kit and nested PCR approaches. Overall, only 1 out of 57 samples was detected to have a mixture of 2 different Mycoplasma species using the later approach. Therefore, we conclude that development of chronic lung disease in Malaysian premature neonates is not due to colonization of Ureaplasma urealyticum or Mycoplasma but other factors.

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