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Asian Journal of Biotechnology
Year: 2013  |  Volume: 5  |  Issue: 1  |  Page No.: 1 - 20

Using Statistical Tools for Improving Bioprocesses

Eutimio Gustavo Fernandez Nunez, Rodolfo Valdes Veliz, Bruno Labate Vale da Costa, Alexandre Goncalves de Rezende and Aldo Tonso    

Abstract: In this review most of statistical tools currently applied in the bioprocess area were discussed and classified. The main three categories were: fair comparison of results, mathematical modeling for little studied systems and taking advantage of large volume of data for enhance robustness and efficiency. For each statistical technique, an example from literature was commented to demonstrate its utility in bioprocess problems. Besides, others statistical tools without a wide application, at the moment, in bioprocess were also discussed, taking into consideration the near future use of them. As a conclusion, a chart was constructed for guiding researchers to select the correct statistical technique according to the specific bioprocess problem.

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