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Asian Journal of Biotechnology
Year: 2011  |  Volume: 3  |  Issue: 1  |  Page No.: 68 - 76

Chemical Composition of Bioactive Compounds by GC-MS Screening and Anti-fungal Properties of the Crude Extracts of Cabbage Samples

M. Amzad Hossain and A. Rahman    

Abstract: The chemical composition of the methanolic crude extract of the leaves of cabbage samples collected from the local market in Dhaka Metropolitan City (DMC), Dhaka, Bangladesh was analysed by GC-MS. It was determined that 44 compounds, which represented 66% of organic compounds, were present in the methanolic crude extract. The methanolic crude extract contained the major compounds mainly phenanthrene, anthracene, oxalic acid, napthalene, β-pinene, 2-octen-3-ol, 3-octamol and 3,4-dihydroxymendelic acid. Thus, the extract was found different types of compounds such as caffice acid and mono, di and tri terpenes and their respective hydrocarbons. Methanol extract of cabbage samples and the derived fractions of hexane, chloroform and ethyl acetate were tested for anti-fungal activity, which was determined by disc diffusion and Minimum Inhibitory Concentration (MIC) determination methods. The methanol extract and the derived fractions of methanol showed great potential of anti-fungal activity as a mycelial growth inhibition against the tested some fungi such as Sclerotium rolfsii, Rhizoctonia solani, Aspergillus niger and Aspergillus fumigatus in the range of 54.6-68.0% and minimum inhibitory concentration ranging from 500-1000 μg mL-1.

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