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Asian Journal of Biochemistry
Year: 2008  |  Volume: 3  |  Issue: 4  |  Page No.: 221 - 227

Antiobesity Effects of Pulp Extract Tamarindus indica in Albino Rat

A.N. Ukwuani, M.G. Abukakar, R.A. Shehu and L.G. Hassan    

Abstract: The pulp extract of Tamarindus indica is used by traditional herbalists as a purgative, drug vehicle and antiobesity agent. The effect of 28 days administration of Tamarindus indica pulp extract on the body weight and lipid profile of the rat was evaluated. There was a significant increase in the weight of the control compared to the treated which significantly decreased (p<0.05) especially the rats given higher doses (2700 to 4500 mg kg-1 body weight). Serum cholesterol and Low Density Lipoprotein (LDL) revealed a significant decrease (p<0.05) while High Density Lipoprotein (HDL) and triglycerides increased in the controlled group compared to the control. Xenical treated group was not significantly different (p<0.05) from the control. Triglycerides significantly increased (p<0.05) and LDL significantly decreased (p<0.05) in the pulp extract treated group as compared to xenical treated group.

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