Abstract: To study the comparative effects of Nano Selenium (Nano-Se) and sodium selenite
on the growth, bioavailability, antioxidative activities, hematological and
biochemical parameters, cellular and humoral immunity, a trial was conducted
on BV 300 layer birds during grower phase (9-20 after weeks) in six treated
groups. After twenth weeks body weight of the all Nano-Se treated groups (up
to a dose of 0.3 mg kg-1 of diet) was found to be significantly (p<0.05)
higher than sodium selenite treated and control groups. However, further increase
in dietary Nano-Se content in feed had negative effect on body weight of bird.
Birds fed with both Nano-Se and sodium selenite showed higher (p<0.05) Se
content in different tissues (Such as breast muscle, liver, kidney, pancreas,
serum and feathers). However, Se content in liver, breast muscle, pancrease
and feathers were signifcantly higher (p<0.05) in Nano-Se treated groups.
In addition, significant (p<0.05) difference was observed as regard to glutathione
peroxidase (GSH-Px), erythrocyte catalase (CAT) and superoxide dismutase (SOD)
activities among the treated groups. Significantly better cellular and humoral
immunity response were observed in Se supplemented birds. Dietary supplementation
of Nano-Se improved the body weight, feed consumption ratio, antioxidant status,
immunity and tissue Se deposition in grower birds. |