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Asian Journal of Animal Sciences
Year: 2011  |  Volume: 5  |  Issue: 4  |  Page No.: 285 - 288

Fungal Mycotoxin (Gliotoxin) Immunomodulating Effects on One-humped Camel (Camelus dromedarius) in Al-Ahsa, Saudi Arabia

M.S. Shathele    

Abstract: The main aim of this study was to determine fungal mycotoxin (Gliotoxin) immunomodulating effects on one-humped camel (Camelus dromedarius) in Al-Hassa, Saudi Arabia. Intravenous administration of 0.05 μg kg-1 gliotoxin for 3 days in camels has significantly resulted in decreased serum total protein, albumin and globulin on day 7 after gliotoxin injection. The toxin also caused reduction of leukocyte, lymphocyte and neutrophil count and lysosomal activity compared to saline treated controls. It is suggested that gliotoxin at a dose of 0.05 μg kg-1 could produce an immunosuppressive effect in the camel.

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