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Research Journal of Medicinal Plants
  Year: 2009 | Volume: 3 | Issue: 4 | Page No.: 134-140
DOI: 10.3923/rjmp.2009.134.140
Biological Activity of Merremia emarginata Crude Extracts in Different Solvents
A.V. Babu, R.S.C. Rao, K.G. Kumar, B.H. Babu and P.V.V. Satyanarayana

Abstract:
The plant Merremia emarginata (Burm. f.) Hallier f., belongs to Convolvulaceae family. In traditional medicinal system, different parts of M. emarginata have been mentioned to be therapeutically used as deobstruent, diuretic, for cough, headache, neuralgia and rheumatism. In the present study, biological activities of different solvent extracts isolated from M. emarginata were tested. Hexane (IA), ethyl acetate (IB), methanol (IC) and aqueous methanol (25%) (ID) extracts of M. emarginata were examined. Antioxidant properties of the extracts were studied by DPPH (1,1-Diphenyl-2-Picrylhydrozyl) radical scavenging activity method and superoxide radical scavenging activity method. Methanol extract exhibited better antioxidant activity than other extracts with IC50 of 8.59 μg mL-1 in DPPH radical scavenging method. Methanol and hexane extracts exhibited α-amylase inhibitory activity with IC50 of 104.5 and 133.4 μg mL-1, respectively. Ethyl acetate extract showed cytotoxicity with ED50 of 34.29 μg mL-1 in brine shrimp lethality assay. The present study revealed that the extracts IB and IC of M. emarginata were found to be showed promising biological activities. Methanol extract of this plant might be use full for antioxidant and antiobesity activities with minimal toxicity.
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COMMENTS
05 April, 2010
bhushan s. bhadan:
dear sir please give me all paper i.e activity perform on this plant and LD50 0f plant. I am waiting for your rply.
 
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