Abstract: To observe pattern of ALP activity in Gingival Crevicular
Fluid (GCF) during canine retraction stage of fixed orthodontic treatment.
Ten patients age between 15 to 27 years old with moderate upper labial
segment crowding were recruited from postgraduate orthodontic clinic.
The tested canines were distalized using nickel titanium push coil spring.
The level of ALP at week 0 acted as the baseline. Samples were taken at
day 0, at week 1, 4, 8 and 12. The activities of ALP were measured using
spectrophotometer (405 nm). Paired sample t-test was used to assess the
differences at weekly interval and between test and control groups over
the study period. The ALP level was decreased in both the mesial and distal
of the test teeth for the first month and stabilizes months after. Significant
difference were detected from week 4 upward when compared to the baseline
(p<0.05). The bony turnover specifically the bone formation can be
monitored through the expression of ALP in the gingival crevicular fluid
during orthodontic treatment.
20 January, 2012
STYLIANOS DALAMPIRAS : Congratulations.I am wondering if we can control the ALP activity in children with retarded eruption of permanent teeth, in comparison with
groups of normal children.