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Trends in Medical Research
  Year: 2012 | Volume: 7 | Issue: 2 | Page No.: 34-42
DOI: 10.3923/tmr.2012.34.42
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Nanotechnology: A Tool to Enhance Therapeutic Values of Natural Plant Products

A. Kumari, V. Kumar and S.K. Yadav

Natural product isolation and extraction is full of many technical hitches. In spite of that plant origin natural products have occupied lead positions as drugs in current pharmacopoeia. In this article, problems in natural product drug development and the possibilities of their improvement through nanoformulations using nanotechnology have been reviewed. Known effects and no side effects have made natural products a powerful therapeutic solution to the organisms. But the delivery of plant origin therapeutic molecules as drugs is problematic due to poor solubility, poor permeability, low bioavailability, instability in biological milieu and extensive first pass metabolism. These limitations of plant origin drugs can be overcome by attaching or encapsulating them with suitable nanomaterials. Nanomaterials can significantly enhance the pharmacokinetics and therapeutic index of plant origin drugs. Targeted delivery and combination therapy can drastically improve the performance of plant origin drugs.
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  •    Surfactant-Free Nanospheres of Methoxy Poly (Ethylene Glycol)-b-Poly (ε-Caprolactone) for Controlled Release of Ibuprofen
  •    Preparation of Surfactant-free Linear and Star-shaped Poly(L-lactide)-b-methoxy Polyethylene Glycol Nanoparticles for Drug Delivery
  •    Phytofabrication and Characterization of Silver Nanoparticles from Piper betle Broth
  •    Methoxy Poly (Ethylene Glycol)-b-Poly (D, L-lactide) Films for Controlled Release of Ibuprofen
How to cite this article:

A. Kumari, V. Kumar and S.K. Yadav, 2012. Nanotechnology: A Tool to Enhance Therapeutic Values of Natural Plant Products. Trends in Medical Research, 7: 34-42.

DOI: 10.3923/tmr.2012.34.42






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