Science Alert
Curve Top
Trends in Medical Research
  Year: 2010 | Volume: 5 | Issue: 1 | Page No.: 1-15
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Prospects for DNA Methylation Research in Psychiatric Disorders

Mohammed A. Ibrahim

Recent advances in molecular genomic analysis showed the possibility of resolving the unexplained mysteries and problems of various biological phenomena. DNA methylation is one of three molecular epigenomic mechanisms involved in controlling gene expression during the process of cellular differentiation, development and aging. This genomic phenomenon has become of great interest in applied research of molecular medicine for its participation in development of various diseases. There is much evidence of possible connection between genomic DNA methylation profiles and psychiatric disorders. Recent studies have demonstrated possible role of DNA methylation in schizophrenia, depression, suicide and bipolar disorder. Aberrations in DNA methylation of several promoter regions of genes have been identified in the genomes of patients with psychiatric disorders. The aim of this effort is to review research work and looking into possible link between abnormal DNA methylation in genomic DNA and psychiatric disorders.
PDF Fulltext XML References Citation Report Citation
  •    Platinum Resistance: The Role of Molecular, Genetic and Epigenetic Factors
  •    An Insight into the Use of Genome, Methylome and Gethylome in Synthetic Biology
  •    Detection of Novel Genomic Polymorphism in Acute Lymphoblastic Leukemia by Random Amplified Polymorphic DNA Analysis
  •    Molecular Analysis of RAPD-PCR Genomic Patterns in Age Related Acute Myeloid Leukemia
  •    Identification of Genomic Markers by RAPD-PCR Primer in Leukemia Patients
How to cite this article:

Mohammed A. Ibrahim , 2010. Prospects for DNA Methylation Research in Psychiatric Disorders. Trends in Medical Research, 5: 1-15.





Curve Bottom