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Research Journal of Phytochemistry
  Year: 2008 | Volume: 2 | Issue: 2 | Page No.: 93-99
 
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Antifungal Triterpenoid Saponins from Lecaniodiscus cupanioides

Sunday A. Adesegun, Herbert A.B. Coker and Mark T. Hamann

Abstract:
Phytochemical investigation of the stems of Lecaniodiscus cupanioides Planch (Sapindaceae) afforded two triterpenoid saponins identified as 3-O- [α-L-arabinofuranosyl-(1→3)- α-L-rhamnopyranosyl- (1→2) - α -L-arabinopyranosyl-]-hederagenin (1) and 3-O- [α -L-arabinopyranosyl- (1→3)- α -L-rhamnopyranosyl (1→2)- α -L-arabinopyranosyl-]-hederagenin (2). The structures of the compounds were determined based on chemical investigations and comprehensive NMR spectroscopic studies including 1H, 13C, DEPT, COSY, HMQC, HMBC, MS and comparison with literature data. The compounds exhibited antifungal activity against C. albicans, C. neoformans and A. fumigatus.
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How to cite this article:

Sunday A. Adesegun, Herbert A.B. Coker and Mark T. Hamann, 2008. Antifungal Triterpenoid Saponins from Lecaniodiscus cupanioides. Research Journal of Phytochemistry, 2: 93-99.

URL: https://scialert.net/abstract/?doi=rjphyto.2008.93.99

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