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Research Journal of Medicinal Plants
  Year: 2012 | Volume: 6 | Issue: 7 | Page No.: 521-528
DOI: 10.3923/rjmp.2012.521.528
 
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Analgesic and Anti-inflammatory Activity of Ethanolic Extract of Zizyphus nummularia

Manoj Goyal, D. Sasmal and B.P. Nagori

Abstract:
Present study was undertaken to examine anti-inflammatory and analgesic activity of ethanolic extract of Zizyphus nummularia (EAZN). EAZN produced anti-inflammatory activity against acute paw oedema induced by carrageenan and histamine at the dose levels of 200 and 300 mg kg-1, at the same dose levels EAZN inhibited peritoneal leukocyte migration. Significant decrease in number of writhes and increase in tail flick latency was observed in acetic acid induced writhing and tail flick test, respectively. In conclusion, it is suggested that inhibition of pain and inflammation mediators is the possible mechanism of action.
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How to cite this article:

Manoj Goyal, D. Sasmal and B.P. Nagori, 2012. Analgesic and Anti-inflammatory Activity of Ethanolic Extract of Zizyphus nummularia. Research Journal of Medicinal Plants, 6: 521-528.

DOI: 10.3923/rjmp.2012.521.528

URL: https://scialert.net/abstract/?doi=rjmp.2012.521.528

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