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Research Journal of Medicinal Plants
  Year: 2012 | Volume: 6 | Issue: 7 | Page No.: 500-510
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Antioxidant and Prebiotic Potential of Some Cucurbits

D. Sharma, I. Rawat and H.C. Goel

The GI tract of an individual which is inhabited by a large number of microbes, is under constant threat from pathogens and oxidative damage. In Indian system of medicine, several cucurbits have been widely documented for prophylactic and therapeutic purposes to ameliorate such situations. The total flavonoids, observed in the extract of three cucurbits, Lagenaria siceraria (Ls), Luffa cylindrica (Lc) and Cucurbita pepo (Cp), were 17.9±1.3, 6.3±0.2 and 2.1±0.5 mg g-1, respectively. The antioxidant activity, determined by DPPH assay, displayed that Ls, Cp and Lc had 77±1.3, 10±3 and 10±1.0% free radical scavenging activity, respectively. Reduction Potential (RP) assay revealed the antioxidant effects for Ls, Lc and Cp as 44±0.8, 22±.3 and 15±.8%, respectively. Maximum activity of quenching H2O2 was demonstrated by Lc (92±1%) as compared to Cp (78±2%) and Ls (76±1.6%). Antimicrobial activity of Lactobacillus rhamnosus measured through generation of inhibition zone against E. coli was augmented maximally in presence of Ls (4.4±0.3 cm), followed by Cp (4.2±.01 cm) and Lc (4.0±.03 cm). Biofilm formation by L. rhamnosus was maximally supported in presence of Lc (absorbance = 0.26±0) followed by Ls (0.21±.01) and Cp (0.20±.01). Thus, these dietary cucurbits showed appreciable antioxidant activity and enhance antimicrobial and barrier function of mucosa by L. rhamnosus and impart protection to gut without any toxic effects.
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  •    Study on Antioxidant Potential of Murraya koenigii Leaves in Wistar Rats
  •    Antioxidant Activity and Pharmacological Evaluation of Cucumis melo var. agrestis Methanolic Seed Extract
  •    A Review on the Medicinally Important Plants of the Family Cucurbitaceae
  •    Antioxidant Activity of Phenolic Rich Fraction Obtained from Convolvulus arvensis L. Leaves Grown in Egypt
  •    Isolation of Anti Ulcer Cucurbitane Type Triterpenoid from the Seeds of Cucurbita pepo
  •    Phytochemical Screening and High Performance TLC Analysis of Some Cucurbits
How to cite this article:

D. Sharma, I. Rawat and H.C. Goel, 2012. Antioxidant and Prebiotic Potential of Some Cucurbits. Research Journal of Medicinal Plants, 6: 500-510.





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