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Research Journal of Medicinal Plants
  Year: 2009 | Volume: 3 | Issue: 4 | Page No.: 141-145
DOI: 10.3923/rjmp.2009.141.145
 
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Effects of Croton penduliflorus Methanolic Extract on Intestinal Enzymes and Protein Content in Pregnant Rats
T.O. Oyesola, F.S. Oluwole and O.A. Oyesola

Abstract: The seeds of Croton penduliflorus (Family Euphorbiaccea) are often used as a purgative. The physiological effects of the methanolic extract on some intestinal disaccharide splitting enzymes were investigated in pregnant rats using an in vivo study. The extract was administered orally at a dose of 550 mg kg-1 body weight during the three phases of pregnancy. The extract caused a significant increase in maltase activity in the three phases of pregnancy, a significant increase in total protein concentration in early and late pregnancy and a significant increase in albumin concentration in early and mid pregnancy (p<0.01). The extract also caused a significant increase in sucrase activity in early pregnancy and in lactase activity in mid pregnancy. The present data suggest that increase activity of disaccharidase brush border enzymes most especially sucrase show that the extract might be having hyperplastic (growth) effect on the small intestinal enzyme activities, there is possibility of increased nutrients to the pregnant rats and fetuses.
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 RELATED ARTICLES:
  •    Effect of Croton penduliflorus on Intestinal Enzymes Activities
  •    Methanolic Extract of Croton Penduliflorus Affects Intestinal Enzyme Activity and Protein Content in the Late Phase of Pregnancy
How to cite this article:

T.O. Oyesola, F.S. Oluwole and O.A. Oyesola, 2009. Effects of Croton penduliflorus Methanolic Extract on Intestinal Enzymes and Protein Content in Pregnant Rats. Research Journal of Medicinal Plants, 3: 141-145.

DOI: 10.3923/rjmp.2009.141.145

URL: https://scialert.net/abstract/?doi=rjmp.2009.141.145
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