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Research Journal of Environmental Toxicology
  Year: 2011 | Volume: 5 | Issue: 2 | Page No.: 152-161
DOI: 10.3923/rjet.2011.152.161
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Effect of Diazinon on Acetylcholinesterase Activity and Lipid Peroxidation of Poecilia reticulata

Archana A. Sharbidre, Vimal Metkari and Priyanka Patode

The present study was undertaken to evaluate the toxicity and effects of a commercial formulation of the organophosphorous insecticide, Diazinon on acetylcholinesterase and lipid peroxidation activity in the freshwater guppy fish Poecilia reticulata. The fish exposed for 96 h to 50, 100 and 150 μg L-1 concentrations of diazinon at 24.0±1.0°C. Some characteristics of this aquarium water were dissolved oxygen, 7.2-7.9 mg L-1 and conductivity, 0.212-0.260 mS. Each exposure involved 3 treatments with 3 replicates and 1 control (without diazinon). In each aquarium (Volume: 5 L) were 10 fishes. Induction of oxidative stress in various tissues was evidence by increased lipid peroxidation levels. Acetylcholinesterase activity responded positively in a concentration dependent pattern, thus, suggesting the use of these two parameters as potential biomarkers of toxicity associated with contaminations exposure in freshwater fishes.
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How to cite this article:

Archana A. Sharbidre, Vimal Metkari and Priyanka Patode, 2011. Effect of Diazinon on Acetylcholinesterase Activity and Lipid Peroxidation of Poecilia reticulata. Research Journal of Environmental Toxicology, 5: 152-161.

DOI: 10.3923/rjet.2011.152.161


18 May, 2012
Esmail Alhemmali:
this abestract is very important, because it has very important information about effect of diazinon to fish




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