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Pakistan Journal of Nutrition
  Year: 2009 | Volume: 8 | Issue: 8 | Page No.: 1199-1203
DOI: 10.3923/pjn.2009.1199.1203
 
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Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats
Emeka, E.J. Iweala and Onyechi Obidoa

Abstract: Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet. Biochemical and hematological parameters investigated included serum protein, total cholesterol, lipid peroxidation, haemoglobin, white blood cells, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-s-transferase and Superoxide dismutase. Histological changes associated with Telfairia occidentalis-supplemented diet on the liver, intestine and testes were also examined. Results showed that Telfairia occidentalis-supplemented diet caused a significant increase (p<0.05) in weight and haemoglobin. Cholesterol and lipid peroxidation were significantly reduced (p<0.05). There were however no significant changes in the enzymes including Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Glutathione-s-transferase and Superoxide dismutase. Only Alkaline phosphatase was significantly reduced (p<0.05). Histological changes showed hypertrophy of the intestinal propia and reduced globlet cells while the testes exhibited thick basement membrane and large spermatogonia.
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How to cite this article:

Emeka, E.J. Iweala and Onyechi Obidoa, 2009. Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats. Pakistan Journal of Nutrition, 8: 1199-1203.

DOI: 10.3923/pjn.2009.1199.1203

URL: https://scialert.net/abstract/?doi=pjn.2009.1199.1203
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