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Pakistan Journal of Biological Sciences
  Year: 2018 | Volume: 21 | Issue: 3 | Page No.: 127-134
DOI: 10.3923/pjbs.2018.127.134
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Health Implications Associated with Aspartame Consumption: A Substantial Review

Ab Qayoom Naik , Tabassum Zafar and Vinoy K Shrivastava


Aspartame, an artificial sweetening agent belongs to dipeptide chemical category with a very strong sweetening potential. Although research findings in humans and non-human primates have demonstrated numerous negative effects of aspartame (biochemical, histological, neurological, behavioral, genetic etc)., the status of aspartame is still debatable. Present manuscript is a critical review of the substantial research findings related to aspartame intake on different research models. Purpose of this review was to spread the awareness about adverse effect of aspartame intake to outline the occurrence of health issues among the population. The process of uptake, storage, compartmentalization and distribution of aspartame within the body is associated with metabolic disorders and various clinical conditions. Available research literature indicates that higher amount of aspartame ingestion should be monitored carefully to avoid health implication within society.

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  •    Effects of Short-term Consumption of Aspartame on Some Biochemical and Hematological Parameters in Female Swiss Albino Mice
  •    Cytotoxic Effect of Aspartame (Diet Sweet) on the Histological and Genetic Structures of Female Albino Rats and Their Offspring
How to cite this article:

Ab Qayoom Naik, Tabassum Zafar and Vinoy K Shrivastava, 2018. Health Implications Associated with Aspartame Consumption: A Substantial Review. Pakistan Journal of Biological Sciences, 21: 127-134.

DOI: 10.3923/pjbs.2018.127.134






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