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Pakistan Journal of Biological Sciences

Year: 2013 | Volume: 16 | Issue: 6 | Page No.: 251-266
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Authors

Shoor Vir Singh

Kuldeep Dhama

Kundan Kumar Chaubey

Naveen Kumar

Pravin Kumar Singh

Jagdip Singh Sohal

Saurabh Gupta

Ajay Vir Singh

Amit Kumar Verma

Ruchi Tiwari

Mahima

S. Chakraborty

Rajib Deb

Keywords

Johne’s disease or Paratuberculosis has emerged as major infectious disease of animals in general and domestic livestock in particular on global basis. There have been major initiatives in developed countries for the control of this incurable malady of animals and human beings alike (inflammatory bowel disease or Crohn’s disease). Disease has not received similar attention due to inherent complexities of disease, diagnosis and control, in resource poor counties around the world. However, the rich genetic diverstiy of the otherwise low productive animal population offers opportunity for the control of Johne’s disease and improve per animal productivity. Present review aims to gather and compile information available on genetics or resistance to Johne’s disease and its future exploitation by resource poor countries rich in animal diversity. This review will also help to create awareness and share knowledge and experience on prevalence and opportunities for control of Johne’s disease in the livestock population to boost per animal productivity among developing and poor countries of the world. Breeding of animals for disease resistance provides good, safe, effective and cheaper way of controlling Johne’s disease in animals, with especial reference to domestic livestock of developing and poor countries. Study will help to establish better understanding of the correlation between host cell factors and resistance to MAP infection which may have ultimately help in the control of Johne’s disease in future.
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How to cite this article

Shoor Vir Singh, Kuldeep Dhama, Kundan Kumar Chaubey, Naveen Kumar, Pravin Kumar Singh, Jagdip Singh Sohal, Saurabh Gupta, Ajay Vir Singh, Amit Kumar Verma, Ruchi Tiwari, Mahima, S. Chakraborty and Rajib Deb, 2013. Impact of Host Genetics on Susceptibility and Resistance to Mycobacterium avium Subspecies Paratuberculosis Infection in Domestic Ruminants. Pakistan Journal of Biological Sciences, 16: 251-266.

DOI: 10.3923/pjbs.2013.251.266

URL: https://scialert.net/abstract/?doi=pjbs.2013.251.266

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