Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2012 | Volume: 15 | Issue: 15 | Page No.: 742-747
DOI: 10.3923/pjbs.2012.742.747
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Effect of Pueraria tuberosa DC. (Indian Kudzu) on Blood Pressure, Fibrinolysis and Oxidative Stress in Patients with Stage 1 Hypertension

S.K. Verma, Vartika Jain and D.P. Singh

Abstract:
The Indian Kudzu (Pueraria tuberosa DC.) is an important medicinal plant widely used in Indian and Chinese traditional systems of medicine. The present study is an attempt to evaluate effect of its tubers on blood pressure, coagulation parameters and antioxidant status in patients with stage 1 (primary) hypertension. In a long term, single blinded, placebo controlled study; 15 patients with stage 1 hypertension (group I), were administered 3 g P. tuberosa in two divided doses while another 15 patients (group II) were administered matched placebo for a period of twelve weeks. A significant fall of 25, 11 and 16 mmHg was observed in systolic (p<0.001), diastolic (p<0.05) and mean (p<0.001) blood pressure, respectively at the end of the study. Along with blood pressure reduction, there was a significant (p<0.01) reduction in plasma fibrinogen and significant enhancement of plasma fibrinolytic activity (p<0.001) and serum total antioxidant status (p<0.05). It was tolerated well without any untoward side effects.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Phytotherapy in Cardiovascular Diseases: From Ethnomedicine to Evidence Based Medicine
  •    Rauvolfia serpentina (L). Benth. ex Kurz.-A Review
  •    Effect of Bombax ceiba Root on Some Cardiovascular Risk Parameters in Patients with Ischemic Heart Disease
How to cite this article:

S.K. Verma, Vartika Jain and D.P. Singh, 2012. Effect of Pueraria tuberosa DC. (Indian Kudzu) on Blood Pressure, Fibrinolysis and Oxidative Stress in Patients with Stage 1 Hypertension. Pakistan Journal of Biological Sciences, 15: 742-747.

DOI: 10.3923/pjbs.2012.742.747

URL: https://scialert.net/abstract/?doi=pjbs.2012.742.747

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 

Curve Bottom