
	Pakistan Journal of Biological Sciences
	Year: 2011 \| Volume: 14 \| Issue: 17 \| Page No.: 844-848 DOI: 10.3923/pjbs.2011.844.848

Common Carotid Artery Intima-media Thickness and Atherosclerotic Plaques in Carotid Bulb in Patients with Chronic Kidney Disease on Hemodialysis: A Case-control Study

Abolhassan Shakeri, Mehdi Abdi, Hamid Tayyebi Khosroshahi and Rohollah Fadaei Fouladi

Abstract: The Common Carotid artery Intima-Media Thickness (CCIMT) can reflect systemic atherosclerosis in renal patients on hemodialysis. This study aimed to compare CCIMT measured by color Doppler ultrasonography between two groups including dialytic patients and normal subjects. In this case-control setting, 48 patients with Chronic Kidney Disease (CKD) on hemodialysis (case group) and 46 age and sex-matched healthy subjects (control group) were enrolled in this study. Color Doppler ultrasound was used to measure CCIMT and determine presence of atherosclerotic plaques in carotid bulb in both groups. Various laboratory parameters were also determined. Serum levels of triglyceride, total cholesterol, low-density lipoprotein, fasting sugar, ionized calcium, inorganic phosphorus and magnesium were comparable between the two groups. Hypertension and elevated levels of serum C-reactive protein, as well as the mean levels of serum non-fasting homocysteine and phosphate were significantly higher in the case group. Mean levels of serum high-density lipoprotein and albumin were significantly higher in the controls. Mean maximum CCIMT was significantly higher in the case group than in controls (0.73±0.15 vs. 0.68±0.08 mm, p = 0.01) even after adjusting for other confounding variables. Frequency of patients with atherosclerotic plaques in carotid bulbs was not significantly different between case and controls. In conclusion, this study showed that CCIMT is significantly higher in CKD patients on hemodialysis comparing with matched normal counterparts. Furthermore, this difference was independent of other conventional risk factors for atherosclerosis.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Red and Black Types of Pepper and Acne Vulgaris: A Case-control Study

•	Berberis vulgaris Juice and Acne Vulgaris: A Placebo-Controlled Study

•	Oral Aqueous Green Tea Extract and Acne Vulgaris: A Placebo-Controlled Study

•	Dark and White Chocolate Consumption and Acne Vulgaris: A Case-Control Study

•	Aloe vera Juice and Acne Vulgaris: A Placebo-Controlled Study

•	Evaluation of Correlation Between Carotid Artery Intima Media Wall Thickness and Coronary Artery Stenosis in Sari, North of Iran

•	Health Related Quality of Life among Egyptian Patients on Hemodialysis

•	Normal Adiponectin Level and Glycemic Control could Delay Subclinical Atherosclerotic Changes in Lean Type 1 Diabetic Children

•	Effects of Heated Vegetable Oils on Serum Lipids and Aorta of Ovariectomized Rats

•	Lipids in Association with Leptin in Maintenance Hemodialysis Patients

How to cite this article:

Abolhassan Shakeri, Mehdi Abdi, Hamid Tayyebi Khosroshahi and Rohollah Fadaei Fouladi, 2011. Common Carotid Artery Intima-media Thickness and Atherosclerotic Plaques in Carotid Bulb in Patients with Chronic Kidney Disease on Hemodialysis: A Case-control Study. Pakistan Journal of Biological Sciences, 14: 844-848.

DOI: 10.3923/pjbs.2011.844.848

URL: https://scialert.net/abstract/?doi=pjbs.2011.844.848

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		AGRIS
		ASCI-Database
		Asian Digital Library
		Cambridge Scientific Abstract
		Chemical Abstract Services
		Google Scholar
		ISI Web of Knowledge
		PubMed
		SCIMAGO
		Thomson ISI

Science Alert