Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2011 | Volume: 14 | Issue: 10 | Page No.: 590-594
DOI: 10.3923/pjbs.2011.590.594
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Evaluation of Serum Levels of Essential Trace Elements in Patients with Pulmonary Tuberculosis Before and After Treatment by Age and Gender

F. Pourfallah, S. Javadian, Z. Zamani, R. Saghiri, S. Sadeghi, B. Zarea, F. Mirkhani, N. Fatemi and T. Kordi

Abstract:
The purpose of this study was to evaluate the levels of Zinc, Copper, Iron and Copper/Zinc ratio in the serum of adult patients with pulmonary tuberculosis in Iran. Serum levels of Zinc and Copper were determined by flame atomic absorption spectrophotometer and serum iron concentration was measured by using an Auto Analyzer. The study group consisted of 50 pulmonary tuberculosis patients before treatment and after 6 months of anti-tubercular therapy. Levels of serum Zn (p<0.001) and Fe (p<0.001) in TB patients were significantly increased after 6 months of anti-tubercular therapy. However, serum Cu concentration (p<0.01) and Cu/Zn ratio (p<0.05) were decreased after 6 months of anti-tubercular therapy. Some studies indicated a strong association of Zn, Cu, Fe and the Cu/Zn ratio with TB. In this study, we found remarkable change in Cu/Zn ratio. Some researchers mentioned that serum Cu/Zn ratio could be used as an important laboratory marker for diagnosis and treatment of tuberculosis. They also mentioned that trace element levels must be closely monitored during the process of disease.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Characteristic of Pulmonary Tuberculosis Patients in Golestan Province of Iran, 2002-2005
  •    Serum Chromium, Copper and Manganese Levels of Diabetic Subjects in Katsina, Nigeria
  •    Copper and Zinc Status in Healthy Volunteers Living in Saudi Arabia
  •    Evaluation of Different Primer Sets for the Rapid Diagnosis of Tuberculosis
How to cite this article:

F. Pourfallah, S. Javadian, Z. Zamani, R. Saghiri, S. Sadeghi, B. Zarea, F. Mirkhani, N. Fatemi and T. Kordi, 2011. Evaluation of Serum Levels of Essential Trace Elements in Patients with Pulmonary Tuberculosis Before and After Treatment by Age and Gender. Pakistan Journal of Biological Sciences, 14: 590-594.

DOI: 10.3923/pjbs.2011.590.594

URL: https://scialert.net/abstract/?doi=pjbs.2011.590.594

COMMENTS
24 January, 2012
bassim ali :
i need to kmow more about this
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 

Curve Bottom