Submit Manuscript

Pakistan Journal of Biological Sciences

Year: 2011 | Volume: 14 | Issue: 10 | Page No.: 572-577
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 540

Search

Authors

R. Taheri

M. Seyedhejazi

M. Ghojazadeh

K. Ghabili

S. Shayeghi

Keywords

Research Article

Comparison of Ketamine and Fentanyl for Postoperative Pain Relief in Children Following Adenotonsillectomy

R. Taheri, M. Seyedhejazi, M. Ghojazadeh, K. Ghabili and S. Shayeghi
Adenotonsillectomy has a high incidence of postoperative pain. Therefore, the purpose of this study was to evaluate the effectiveness and safety of either ketamine or fentanyl for postoperative pain relief in children following adenotonsillectomy. Sixty children aged 3-12 years, scheduled for adenotonsillectomy, were enrolled in this randomized, double-blind study. Patients were divided into two groups of 30 cases and received intravenous ketamine (0.5 mg kg-1) or fentanyl (1 μg kg-1). Modified Hannallah pain scale or Observational Pain Scores (OPS), nausea, vomiting, bleeding, rescue analgesia, sedation and post-anesthesia recovery scores were recorded both at first and 15th minute postoperatively. Moreover, patients receiving ketamine (group 1) or fentanyl (group 2) had comparable OPS and sedation score both on arrival and at 15th minute in the recovery room (p>0.05). Although rescue analgesics were similarly required in both groups (p>0.05), the time to reach rescue analgesia was shorter in group 1 (p = 0.001). Only one patient in fentanyl group had nausea and vomiting in the first 15 min that needed antiemetic in the recovery room. In conclusion, intravenous fentanyl (1 μg kg-1) compared with intravenous ketamine (0.5 mg kg-1) might provide extended time to first analgesic in children undergoing adenotonsillectomy. Interestingly, fentanyl and ketamine did not differ in post-operative vomiting.
PDF Fulltext XML References Citation

Related Articles

Effect of Increased Dose of Dexmedetomidine Vis-à-vis Addition of Fentanyl on Clinical and Cardio-respiratory Actions of Dexmedetomidine-midazolam-ketamine Anaesthesia in Dogs
Comparison of Midazolam with Lidocaine and Fentanyl for Caudal Analgesia in Children
Assessment the Effect of Midazolam Sedation on Hypoxia During Upper Gastrointestinal Endoscopy
Ketamine as an Adjuvant to Morphine for Patient Controlled Analgesia in Morbidly Obese Patients
Comparing Propofol-ephedrine with Propofol-saline on Intubating Conditions after Priming by Atracurium
Effect of Scalp Infiltration with Bupivacaine on Early Hemodynamic Responses during Craniotomy under General Anesthesia

Leave a Comment

Your email address will not be published. Required fields are marked *