Submit Manuscript

Pakistan Journal of Biological Sciences

Year: 2010 | Volume: 13 | Issue: 15 | Page No.: 743-747
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 91

Authors

K.N. Dailami

M. Azadbakht

Z.R. Pharm

M. Lashgari

Keywords

Research Article

Prevention of Selenite-induced Cataractogenesis by Origanum vulgare Extract

K.N. Dailami, M. Azadbakht, Z.R. Pharm and M. Lashgari
The present study sought to assess antioxidant effect of Origanum vulgare extract in preventing selenite-induced cataractogenesis. This study was performed on Young white rats received sodium selenite (30 nmol g-1 birth weight) subcutaneously on day 13 post partum during two months in 2009. Cataract formation and intensity was detected and measured by slit-lamp. Origanum vulgare (Ov) extract (2 g kg-1) was given (1-2 times) intraperitoneal at different times with respect to the selenite administration lens opacification was analyzed in selenite, selenite-Ov, Ov and control groups on day 7 after selenite administration. Ov extract have revealed a significant protective effect against selenite induced cataract when injected 1 and 2 day (2 times) before selenite injection. There is a protective effect of Ov against selenite induced cataract formation. It is supposed that the anticataract effect of Ov extract could be based on direct or indirect antioxidant mechanisms.
PDF Fulltext XML References Citation

Leave a Comment

Your email address will not be published. Required fields are marked *