Submit Manuscript

Pakistan Journal of Biological Sciences

Year: 2009 | Volume: 12 | Issue: 1 | Page No.: 87-90
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 223

Authors

N. Ara

M.H. Nur

M.S. Amran

M.I.I. Wahid

M. Ahmed

Keywords

Research Article

In vitro Antimicrobial and Cytotoxic Activities of Leaves and Flowers Extracts from Lippia alba

N. Ara, M.H. Nur, M.S. Amran, M.I.I. Wahid and M. Ahmed
The research was conducted to investigate the in vitro antimicrobial and cytotoxic activities of leaves and flowers extract extracted from Lippia alba. Disc diffusion technique was used for in vitro antibacterial and antifungal screening. Zones of inhibition were observed in disc diffusion for antibacterial screening against 4 Gram-positive pathogenic and 6 Gram-negative pathogenic bacteria. Among crude extracts chloroform extract showed good activity against all test organisms. A Large zone of inhibition was observed (18 mm) against Vibrio parahaemolyticus. In antifungal screening, the compound showed mild to moderate zones of inhibition against four tested organisms. A Large zone of inhibition was observed against Aspergillus niger (13 mm). Cytotoxic activities of crude extracts were determined using Brine shrimp lethality Bioassay and LC 50 values of standard Vincristin sulphate as positive control, n-hexane and crude ethanol extracts were found to be 5, 15 and 20 μg mL-1, respectively.
PDF Fulltext XML References Citation

Leave a Comment

Your email address will not be published. Required fields are marked *