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Pakistan Journal of Biological Sciences

Year: 2008 | Volume: 11 | Issue: 23 | Page No.: 2634-2638
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Authors

F. Shishehbor

A. Mansoori

A.R. Sarkaki

M.T. Jalali

S.M. Latifi

Keywords

In this study, the effect of apple cider vinegar on Fasting Blood Glucose (FBG), glycated haemoglobin (HbA1c) and lipid profile in normal and diabetic rats was investigated. Diabetes was induced in male Wistar rats (300±30 g) by the intraperitoneal injection of streptozotocin (60 mg kg-1 of body weight). Both normal and diabetic animals were fed with standard animal food containing apple cider vinegar (6% w/w) for 4 weeks. Fasting blood glucose did not change, while HbA1c significantly decreased by apple cider vinegar in diabetic group (p<0.05). In normal rats fed with vinegar, significant reduction of low density lipoprotein-cholesterol (LDL-c) (p<0.005) and significant increase of high density lipoprotein-cholesterol (HDL-c) levels (p<0.005) were observed. Apple cider vinegar also reduced serum triglyceride (TG) levels (p<0.005) and increased HDL-c (p<0.005) in diabetic animals. These results indicate that apple cider vinegar improved the serum lipid profile in normal and diabetic rats by decreasing serum TG, LDL-c and increasing serum HDL-c and may be of great value in managing the diabetic complications.
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Comments

Niz Thaha - Singapore Reply

Very useful paper in our study.
However, we wish to know what is the active ingredient found in the apple juice, and the variety of apple suitable as effective (red or green).
Also if apple vinegar is applicable to Type 1 or 2 diabetic patients.
Further research is highly recommended and we are willing to be partners in your study.
Regards / niz

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