Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Pharmacology and Toxicology
  Year: 2014 | Volume: 9 | Issue: 2 | Page No.: 90-96
DOI: 10.3923/jpt.2014.90.96
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Toxic Effect of Potassium Dichromate on Sex Hormones and Possible Protective Effect of Rice Bran Oil in Female Albino Rats

Mohammed Fathy Assasa and Mohammed Mohammed Ibrahim Farahat

Abstract:
This study was established to investigate the toxic effects of potassium dichromate on sex hormones of female albino rats and the possible protective effects of rice bran oil. This study was carried out on thirty weanling mature female albino rats weighing between 120 and 140 g, divided randomly into 3 groups. Rats in the 1st group were used as a control (group C ), the 2nd group of rats (group E) received Potassium dichromate (20 mg kg-1, I/P) for 5 months, while the 3rd group, group B, received both Potassium dichromate solution (20 mg kg-1, I/P) and rice bran oil (20 mg kg-1), with 1 h in between for 5 months. Blood samples were collected from retro orbital venous sinus in lithium heparin tubes every 30 days. Sexual hormones were determined by ELISA technique. The study showed that potassium dichromate affects the levels of sex hormones and that the rice bran oil has great effects in the prevention of the toxic effects of potassium dichromate on sex hormones.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Comparative Effect of Vitamins A and E on Gasoline Vapours-Induced Haematotoxicity and Weight-Loss in Male Rats
How to cite this article:

Mohammed Fathy Assasa and Mohammed Mohammed Ibrahim Farahat, 2014. Toxic Effect of Potassium Dichromate on Sex Hormones and Possible Protective Effect of Rice Bran Oil in Female Albino Rats. Journal of Pharmacology and Toxicology, 9: 90-96.

DOI: 10.3923/jpt.2014.90.96

URL: https://scialert.net/abstract/?doi=jpt.2014.90.96

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

Curve Bottom