• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. Journal of Pharmacology and Toxicology
  2. Vol 6 (1), 2011
  3. 62-68
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

Journal of Pharmacology and Toxicology

Year: 2011 | Volume: 6 | Issue: 1 | Page No.: 62-68
DOI: 10.3923/jpt.2011.62.68

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 226

Authors


S.A. Ali

Country: Sudan

A.A. Gameel

Country: Sudan

A.H. Mohamed

Country: Sudan

T. Hassan

Country: Sudan

Keywords


  • Hepatoprotective activity
  • Capparis decidua
  • rats
  • CCl4
Research Article

Hepatoprotective Activity of Capparis decidua Aqueous and Methanolic Stems Extracts Against Carbon Tetrachloride Induced Liver Histological Damage in Rats

S.A. Ali, A.A. Gameel, A.H. Mohamed and T. Hassan
In this study, hepatoprotective effect of aqueous and methanolic extracts of Capparis decidua stems were evaluated against carbon tetrachloride induced liver damage in rats. Simultaneous oral administration of both extracts (200, 400 mg kg-1) with CCl4 in paraffin oil (1:9 v/v) at a dose of 0.2 mL kg-1 for 10 days covered the liver fatty changes induced by the hepatotoxic compound observed in the intoxicated control rats. Slight to mild changes in hepatocytes were observed in rats dosed by aqueous extract of C. decidua stems and higher dose of methanolic extract, whereas the lower dose of methanolic extract revealed more severe lesions than the higher dose. The results were compared with the hepatoprotective effect of the standard drug silymarin.
PDF Fulltext XML References Citation

How to cite this article

S.A. Ali, A.A. Gameel, A.H. Mohamed and T. Hassan, 2011. Hepatoprotective Activity of Capparis decidua Aqueous and Methanolic Stems Extracts Against Carbon Tetrachloride Induced Liver Histological Damage in Rats. Journal of Pharmacology and Toxicology, 6: 62-68.

DOI: 10.3923/jpt.2011.62.68

URL: https://scialert.net/abstract/?doi=jpt.2011.62.68

Related Articles

Nephroprotective Activity of Capparis decidua Aerial Parts Methanolic Extract in Wistar Albino Rats
Hepatoprotective Activity and Flavonoids of Alchornea laxiflora Leaf Extract
Hepatoprotective Effect of Aqueous Leave Extract of Cyphostemma glaucophilla on Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats
Investigation of Rutin Content in Different Plant Parts of Wild Caper (Capparis spinosa L.) Populations from Jordan
Hepatoprotective Activity of Aqueous and Methanolic Extracts of Capparis decidua Stems Against Carbon Tetrachloride Induced Liver Damage in Rats

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved