
	Journal of Pharmacology and Toxicology
	Year: 2011 \| Volume: 6 \| Issue: 1 \| Page No.: 62-68 DOI: 10.3923/jpt.2011.62.68

Hepatoprotective Activity of Capparis decidua Aqueous and Methanolic Stems Extracts Against Carbon Tetrachloride Induced Liver Histological Damage in Rats

S.A. Ali, A.A. Gameel, A.H. Mohamed and T. Hassan

Abstract: In this study, hepatoprotective effect of aqueous and methanolic extracts of Capparis decidua stems were evaluated against carbon tetrachloride induced liver damage in rats. Simultaneous oral administration of both extracts (200, 400 mg kg^-1) with CCl₄ in paraffin oil (1:9 v/v) at a dose of 0.2 mL kg^-1 for 10 days covered the liver fatty changes induced by the hepatotoxic compound observed in the intoxicated control rats. Slight to mild changes in hepatocytes were observed in rats dosed by aqueous extract of C. decidua stems and higher dose of methanolic extract, whereas the lower dose of methanolic extract revealed more severe lesions than the higher dose. The results were compared with the hepatoprotective effect of the standard drug silymarin.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Hepatoprotective Activity and Flavonoids of Alchornea laxiflora Leaf Extract

•	Hepatoprotective Effect of Aqueous Leave Extract of Cyphostemma glaucophilla on Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats

•	Investigation of Rutin Content in Different Plant Parts of Wild Caper (Capparis spinosa L.) Populations from Jordan

•	Hepatoprotective Activity of Aqueous and Methanolic Extracts of Capparis decidua Stems Against Carbon Tetrachloride Induced Liver Damage in Rats

How to cite this article:

S.A. Ali, A.A. Gameel, A.H. Mohamed and T. Hassan, 2011. Hepatoprotective Activity of Capparis decidua Aqueous and Methanolic Stems Extracts Against Carbon Tetrachloride Induced Liver Histological Damage in Rats. Journal of Pharmacology and Toxicology, 6: 62-68.

DOI: 10.3923/jpt.2011.62.68

URL: https://scialert.net/abstract/?doi=jpt.2011.62.68

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Cambridge Scientific Abstract
		Chemical Abstract Services
		Google Scholar

Science Alert