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Journal of Pharmacology and Toxicology
  Year: 2011 | Volume: 6 | Issue: 1 | Page No.: 18-23
DOI: 10.3923/jpt.2011.18.23
 
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Toxic Effect of Ipomoea carnea Leaves on Wistar Rats

A.A. Amna, E.H. Abdelgadir and S.E.I. Adam

Abstract:
Ipomoea carnea is known as an ornamental hedge plant in Sudan. The leaves of ipomoea carnea were fed to male wistar rats at 2 and 10% of standard diet for 21 days. Locomotor disturbance, loss of hair and reflexes and interohepatonephropathy were observed in the rats fed a diet containing 10% I. carnea leaves, these changes were accompanied by leukocytosis, anemia and increases in serum aspartate Amino Transferase (AST) activity and urea concentration and by decreased albumin level. The effect on rats fed a diet containing 2% I. carnea leaves is less marked.
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How to cite this article:

A.A. Amna, E.H. Abdelgadir and S.E.I. Adam, 2011. Toxic Effect of Ipomoea carnea Leaves on Wistar Rats. Journal of Pharmacology and Toxicology, 6: 18-23.

DOI: 10.3923/jpt.2011.18.23

URL: https://scialert.net/abstract/?doi=jpt.2011.18.23

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